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Perhexiline

Chemical Structure : Perhexiline

CAS No.: 6621-47-2

Perhexiline

Catalog No.: PC-62687Not For Human Use, Lab Use Only.

Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).

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Biological Activity

Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2).
Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth.
Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.

Physicochemical Properties

M.Wt 277.496
Formula C19H35N
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2,2-dicyclohexylethyl)-piperidine

References

1. Guo Y, et al. J Clin Invest. 2015 Oct 1;125(10):3819-30.

2. Hamdan M, et al. Pharmacol Res. 2001 Aug;44(2):99-104.

3. Ren XR, et al. Breast Cancer Res. 2015 Feb 15;17:20.

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