Chemical Structure : PfHsp70-1 inhibitor AMK3
Catalog No.: PC-27251Not For Human Use, Lab Use Only.
PfHsp70-1 inhibitor AMK3 is a potent, high affinity and selective inhibitor of Plasmodium falciparum chaperone PfHsp70-1 with MST Kd of 0.82 uM, binds to the PfHsp70-1 N-terminal NBD and competes for ATP binding, has >25-fold for PfHsp70-1 over the human homolog HSPA1A.
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PfHsp70-1 inhibitor AMK3 is a potent, high affinity and selective inhibitor of Plasmodium falciparum chaperone PfHsp70-1 with MST Kd of 0.82 uM, binds to the PfHsp70-1 N-terminal NBD and competes for ATP binding, has >25-fold for PfHsp70-1 over the human homolog HSPA1A.
| M.Wt | 395.43 | |
| Formula | C22H17N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Keeler AM, et al. Antimicrob Agents Chemother. 2026 Jul 2:e0046626.

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