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PhiKan083

Chemical Structure : PhiKan083

CAS No.: 880813-36-5

PhiKan083 (PhiKan-083, PhiKan 083)

Catalog No.: PC-25767Not For Human Use, Lab Use Only.

PhiKan083 (PhiKan 083) is a specific reactivator and stabilizer and reactivator of p53 Y220C mutant with dissociation constant of 150 uM, binds to the surface cavity and stabilizes p53 Y220C..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PhiKan083 (PhiKan 083) is a specific reactivator and stabilizer and reactivator of p53 Y220C mutant with dissociation constant of 150 uM, binds to the surface cavity and stabilizes p53 Y220C.

Physicochemical Properties

M.Wt 238.33
Formula C16H18N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine

References

1. Boeckler FM, et al. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10360-5.

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