Chemical Structure : Picrotoxin
CAS No.: 124-87-8
Catalog No.: PC-23662Not For Human Use, Lab Use Only.
Picrotoxin (Cocculin) is a natural noncompetitive antagonist of GABAA receptor (GABA AR), binds to the interface pocket on the GABAR, causes overstimulation and induces convulsions.
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Picrotoxin (Cocculin) is a natural noncompetitive antagonist of GABAA receptor (GABA AR), binds to the interface pocket on the GABAR, causes overstimulation and induces convulsions.
M.Wt | ||
Formula | C15H18O7.C15H16O6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-, compd. with (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-hexahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione (1:1) |
1. Boulanger JJ, et al. Neuroscience. 2017 Aug 18. pii: S0306-4522(17)30584-5.
2. Carpenter TS, et al. Chem Res Toxicol. 2013 Oct 21;26(10):1444-54.
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