Catalog No.: PC-20782Not For Human Use, Lab Use Only.
Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor.
Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca).
Physicochemical Properties
M.Wt
415.57
Formula
C25H37NO4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
References
1. Bridges HR, et al. Nat Commun. 2020 Oct 16;11(1):5261.
2. Baradaran R, et al. Nature. 2013;494:443–448.
3. Horgan DJ, et al. J. Biol. Chem. 1968;243:5967–5976.
