Pifithrin-α hydrobromide | p53 inhibitor

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Chemical Structure : Pifithrin-α hydrobromide

CAS No.: 63208-82-2

Pifithrin-α hydrobromide (Pifithrin hydrobromide, PFTα hydrobromide)

Catalog No.: PC-22247Not For Human Use, Lab Use Only.

Pifithrin-α hydrobromide is a small molecule inhibitor of p53, blocks its transcriptional activity and prevents cells from apoptosis, also is an aryl hydrocarbon receptor (AhR) agonist.

Packing	Price	Stock
5 mg (Free Sample)	$18	In stock
10 mg	$98	In stock
25 mg	$158	In stock
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Biological Activity

Pifithrin-α hydrobromide is a small molecule inhibitor of p53, blocks its transcriptional activity and prevents cells from apoptosis, also is an aryl hydrocarbon receptor (AhR) agonist.

Physicochemical Properties

M.Wt	367.31
Formula	C16H19BrN2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone Hydrobromide

References

1. Yu W, et al. Int J Biol Sci. 2016 Jan 1;12(2):198-209.

2. Hoagland MS, et al. J Pharmacol Exp Ther. 2005 Aug;314(2):603-10.

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Pifithrin-α hydrobromide (Pifithrin hydrobromide, PFTα hydrobromide)

Biological Activity

Physicochemical Properties

References

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