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Pifithrin-α hydrobromide

Chemical Structure : Pifithrin-α hydrobromide

CAS No.: 63208-82-2

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Pifithrin-α hydrobromide (Pifithrin hydrobromide, PFTα hydrobromide)

Catalog No.: PC-22247Not For Human Use, Lab Use Only.

Pifithrin-α hydrobromide is a small molecule inhibitor of p53, blocks its transcriptional activity and prevents cells from apoptosis, also is an aryl hydrocarbon receptor (AhR) agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pifithrin-α hydrobromide is a small molecule inhibitor of p53, blocks its transcriptional activity and prevents cells from apoptosis, also is an aryl hydrocarbon receptor (AhR) agonist.

Physicochemical Properties

M.Wt 367.31
Formula C16H19BrN2OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone Hydrobromide

References

1. Yu W, et al. Int J Biol Sci. 2016 Jan 1;12(2):198-209.

2. Hoagland MS, et al. J Pharmacol Exp Ther. 2005 Aug;314(2):603-10.

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