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Chemical Structure : Pimelic Diphenylamide 106
CAS No.: 937039-45-7
Catalog No.: PC-45618Not For Human Use, Lab Use Only.
Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657) is a slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657) is a slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively).
Pimelic Diphenylamide 106 shows weak inhibition on HDAC8 (IC50=5 uM).
Pimelic Diphenylamide 106 has preference toward HDAC3.
| M.Wt | 339.4314 | |
| Formula | C20H25N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 25 mg/mL |
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| Chemical Name/SMILES |
Heptanediamide, N1-(2-aminophenyl)-N7-(4-methylphenyl)- |
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1. Chou CJ, et al. J Biol Chem. 2008 Dec 19;283(51):35402-9.
2. Xu C, et al. Chem Biol. 2009 Sep 25;16(9):980-9.
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