You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-HDAC-Pimelic Diphenylamide 106
Pimelic Diphenylamide 106

Chemical Structure : Pimelic Diphenylamide 106

CAS No.: 937039-45-7

Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657)

Catalog No.: PC-45618Not For Human Use, Lab Use Only.

Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657) is a slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively).

Packing Price Stock Quantity
10 mg $88 In stock
25 mg $138 In stock
50 mg $218 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657) is a slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively).
Pimelic Diphenylamide 106 shows weak inhibition on HDAC8 (IC50=5 uM).
Pimelic Diphenylamide 106 has preference toward HDAC3.

Physicochemical Properties

M.Wt 339.4314
Formula C20H25N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 25 mg/mL

Chemical Name/SMILES

Heptanediamide, N1-(2-aminophenyl)-N7-(4-methylphenyl)-

References

1. Chou CJ, et al. J Biol Chem. 2008 Dec 19;283(51):35402-9.

2. Xu C, et al. Chem Biol. 2009 Sep 25;16(9):980-9.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: