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Pinoresinol

Chemical Structure : Pinoresinol

CAS No.: 487-36-5

Pinoresinol ((+)-Pinoresinol)

Catalog No.: PC-27917Not For Human Use, Lab Use Only.

Pinoresinol ((+)-Pinoresinol) is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds, shows inhibitory activity against rat intestinal α-glucosidase with IC50 of 34.3 uM, inhibits proliferation and induces differentiation on human HL60 leukemia cells, also exerts enzymatic β-glucuronidase inhibitory activity with IC50 of 27.9 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pinoresinol ((+)-Pinoresinol) is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds, shows inhibitory activity against rat intestinal α-glucosidase with IC50 of 34.3 uM, inhibits proliferation and induces differentiation on human HL60 leukemia cells, also exerts enzymatic β-glucuronidase inhibitory activity with IC50 of 27.9 uM.

Physicochemical Properties

M.Wt 358.39
Formula C20H22O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,4'-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol)

References

1. Chen CC, et al. Planta Med. 1999 Dec;65(8):709-11.

2. Wikul A, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5215-7.

3. Wang GK, et al. Nat Prod Res. 2013 Aug;27(15):1348-52.

4. Nishikawa S, et al. J Nat Med. 2026 Jul 28. doi: 10.1007/s11418-026-02070-1.

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