Chemical Structure : Pioglitazone
CAS No.: 111025-46-8
Catalog No.: PC-26222Not For Human Use, Lab Use Only.
Pioglitazone (U 72107) is an orally active and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively, highly selective over PPARα and PPARδ
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Pioglitazone (U 72107) is an orally active and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively, highly selective over PPARα and PPARδ
| M.Wt | 356.44 | |
| Formula | C19H20N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione |
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1. Kubota N, et al. J Biol Chem. 2006 Mar 31;281(13):8748-55.
2. Puddu A, et al. Regul Pept. 2012 Aug 20;177(1-3):79-84.

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