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Pioglitazone

Chemical Structure : Pioglitazone

CAS No.: 111025-46-8

Pioglitazone (U-72107, U72107)

Catalog No.: PC-26222Not For Human Use, Lab Use Only.

Pioglitazone (U 72107) is an orally active and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively, highly selective over PPARα and PPARδ

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pioglitazone (U 72107) is an orally active and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively, highly selective over PPARα and PPARδ

Physicochemical Properties

M.Wt 356.44
Formula C19H20N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione

References

1. Kubota N, et al. J Biol Chem. 2006 Mar 31;281(13):8748-55.

2. Puddu A, et al. Regul Pept. 2012 Aug 20;177(1-3):79-84.

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