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Chemical Structure : Piromelatine
CAS No.: 946846-83-9
Catalog No.: PC-61335Not For Human Use, Lab Use Only.
Piromelatine (Neu-P11) is a melatonin melatonin receptor MT1/MT2 and serotonin 5-HT1A/5-HT1D receptor agonist.
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|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
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Piromelatine (Neu-P11) is a melatonin melatonin receptor MT1/MT2 and serotonin 5-HT1A/5-HT1D receptor agonist.
Piromelatine inhibits weight gain and improves insulin sensitivity in high-fat/high-sucrose-fed rats。
Piromelatine facilitates memory performance and improves cognitive impairment in a rat model of Alzheimer' disease.
| M.Wt | 312.32 | |
| Formula | C17H16N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-4-oxo-4H-pyran-2-carboxamide |
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1. She M, et al. Eur J Pharmacol. 2014 Mar 15;727:60-5.
2. Liu YY, et al. Psychopharmacology (Berl). 2014 Oct;231(20):3973-85.
3. She M, et al. Pharmacol Res. 2009 Apr;59(4):248-53.
4. Zhou J, et al. J Pharmacol Exp Ther. 2018 Jan;364(1):55-69.
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