Chemical Structure : Pomalidomide
CAS No.: 19171-19-8
Catalog No.: PC-42764Not For Human Use, Lab Use Only.
Pomalidomide (CC4047) is a potent IKZF1 degrader with DC50 of 6 nM and Dmax=86%, has no effect on IKZF2 protein levels up to 50 μM.
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M.Wt | 273.2441 | |
Formula | C13H11N3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)- |
1. Muller GW, et al. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1625-30.
2. Payvandi F, et al. Cell Immunol. 2004 Aug;230(2):81-8.
3. Galustian C, et al. Cancer Immunol Immunother. 2009 Jul;58(7):1033-45.
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