Chemical Structure : Pralatrexate
CAS No.: 146464-95-1
Catalog No.: PC-42590Not For Human Use, Lab Use Only.
An antifolate that fuctions as a dihydrofolate reductase inhibitor for treatment of several malignancies..
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An antifolate that fuctions as a dihydrofolate reductase inhibitor for treatment of several malignancies.
Chemotherapeutic Agents
Approved
M.Wt | 477.4726 | |
Formula | C23H23N7O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]- |
1. DeGraw JI, et al. J Med Chem. 1993 Jul 23;36(15):2228-31.
2. Krug LM, et al. Clin Cancer Res. 2000 Sep;6(9):3493-8.
3. Wang ES, et al. Leuk Lymphoma. 2003 Jun;44(6):1027-35.
4. Molina JR. IDrugs. 2008 Jul;11(7):508-21.
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