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Chemical Structure : Prinomastat
CAS No.: 192329-42-3
Catalog No.: PC-62944Not For Human Use, Lab Use Only.
Prinomastat (AG3340) is a potent, selective MMP inhibitor with pM affinities for inhibiting gelatinases (MMP-2 and -9, Ki=50-150 pM), MMP-14 and MMP-13.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Prinomastat (AG3340) is a potent, selective MMP inhibitor with pM affinities for inhibiting gelatinases (MMP-2 and -9, Ki=50-150 pM), MMP-14 and MMP-13.
AG3340 demonstrates broad antitumor activity in a number of tumor models, inhibits glioma invasion or growth of the human malignant glioma cell line U87.
AG3340 also suppresses tumor growth in a malignant glioma tumor model.
| M.Wt | 423.502 | |
| Formula | C18H21N3O5S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-Thiomorpholinecarboxamide, N-hydroxy-2,2-dimethyl-4-[[4-(4-pyridinyloxy)phenyl]sulfonyl]-, (S)- |
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1. Price A, et al. Clin Cancer Res. 1999 Apr;5(4):845-54.
2. Santos O, et al. Clin Exp Metastasis. 1997 Sep;15(5):499-508.
3. Shalinsky DR, et al. Ann N Y Acad Sci. 1999 Jun 30;878:236-70.
4. Shalinsky DR, et al. Clin Cancer Res. 1999 Jul;5(7):1905-17.
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