Probenecid

Chemical Structure : Probenecid

CAS No.: 57-66-9

Catalog No.: PC-28017Not For Human Use, Lab Use Only.

Probenecid is a potent and specific activator of transient receptor potential vanilloid 2 (TRPV2) channel with EC50 of 31.9 uM, shows no activity against TRPV1, TRPV3, TRPV4, TRPM8 and TRPA1 channels.

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Biological Activity

Probenecid is a potent and specific activator of transient receptor potential vanilloid 2 (TRPV2) channel with EC50 of 31.9 uM, shows no activity against TRPV1, TRPV3, TRPV4, TRPM8 and TRPA1 channels.

Physicochemical Properties

M.Wt	285.36
Formula	C13H19NO4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 4-[(dipropylamino)sulfonyl]-

References

1. Bang S, et al. Neurosci Lett. 2007 Sep 25;425(2):120-5.

2. Rocereta JA, et al. Nat Struct Mol Biol. 2025 Jun;32(6):1019-1029.

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Probenecid

Biological Activity

Physicochemical Properties

References

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