Catalog No.: PC-73357Not For Human Use, Lab Use Only.
Pyridostatin (RR82) is a high-affinity G-quadruplex-stabilizing small molecule (Kd=490 nM), promotes the folding of telomeric G-quadruplexes, induces DNA damage and cell cycle arrest.
Pyridostatin (RR82) is a high-affinity G-quadruplex-stabilizing small molecule (Kd=490 nM), promotes the folding of telomeric G-quadruplexes, induces DNA damage and cell cycle arrest.
Pyridostatin targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells.
Pyridostatin also targets telomeric G-quadruplexes, inducing telomerase dysfunction.
Pyridostatin activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).
Pyridostatin decreases the Epstein-Barr virus-encoded nuclear antigen 1 (EBNA1) synthesis.
