Pyridoxal Isonicotinoyl Hydrazone

Chemical Structure : Pyridoxal Isonicotinoyl Hydrazone

CAS No.: 737-86-0

Catalog No.: PC-27602Not For Human Use, Lab Use Only.

Pyridoxal isonicotinoyl hydrazone (PIH) is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions.

Packing	Price	Stock
10 mg	$48	In stock
25 mg	$78	In stock
50 mg	$118	In stock
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Biological Activity

Pyridoxal isonicotinoyl hydrazone (PIH) is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions.

Physicochemical Properties

M.Wt	286.29
Formula	C14H14N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide

References

1. Ponka P, et al. Blood. 1985 Apr;65(4):850-7.

2. Hermes-Lima M, et al. Biochim Biophys Acta. 2000 Oct 18;1523(2-3):154-60.

3. Landschulz W, et al. J Cell Biol. 1984 Feb;98(2):596-601.

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