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Pyronaridine

Chemical Structure : Pyronaridine

CAS No.: 74847-35-1

Pyronaridine

Catalog No.: PC-72957Not For Human Use, Lab Use Only.

Pyronaridine is a fast-acting (chloroquine-like) drug that has the demonstrated ability to inhibit P. falciparum β-hematin formation in vitro, suppress the selection of M5717-resistant mutants.

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Biological Activity

Pyronaridine is a fast-acting (chloroquine-like) drug that has the demonstrated ability to inhibit P. falciparum β-hematin formation in vitro, suppress the selection of M5717-resistant mutants.

Physicochemical Properties

M.Wt 518.058
Formula C29H32ClN5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino)-2,6-bis(pyrrolidin-1-ylmethyl)phenol

References

1. Arez F, et al. ACS Infect Dis. 2019 Nov 8;5(11):1831-1842.

2. Rottmann M, et al. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02181-19.

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