Pyronaridine

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Chemical Structure : Pyronaridine

CAS No.: 74847-35-1

Catalog No.: PC-72957Not For Human Use, Lab Use Only.

Pyronaridine is a fast-acting (chloroquine-like) drug that has the demonstrated ability to inhibit P. falciparum β-hematin formation in vitro, suppress the selection of M5717-resistant mutants.

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100 mg	$58	In stock
500 mg	$98	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pyronaridine is a fast-acting (chloroquine-like) drug that has the demonstrated ability to inhibit P. falciparum β-hematin formation in vitro, suppress the selection of M5717-resistant mutants.

Physicochemical Properties

M.Wt	518.058
Formula	C29H32ClN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino)-2,6-bis(pyrrolidin-1-ylmethyl)phenol

References

1. Arez F, et al. ACS Infect Dis. 2019 Nov 8;5(11):1831-1842.

2. Rottmann M, et al. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02181-19.

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Pyronaridine

Biological Activity

Physicochemical Properties

References

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