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Pyruvate Carboxylase-IN-1

Chemical Structure : Pyruvate Carboxylase-IN-1

CAS No.: 70205-50-4

Pyruvate Carboxylase-IN-1

Catalog No.: PC-27059Not For Human Use, Lab Use Only.

Pyruvate Carboxylase-IN-1 (Compound 37) is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 204 nM and 104 nM for PC in cell lysates and cells, shows antiproliferative activity against human hepatocellular carcinoma (HCC).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Pyruvate Carboxylase-IN-1 (Compound 37) is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 204 nM and 104 nM for PC in cell lysates and cells, shows antiproliferative activity against human hepatocellular carcinoma (HCC).

Physicochemical Properties

M.Wt 242.27
Formula C15H14O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Methoxy-9,10-dihydrophenanthrene-4,5-diol

References

1. Yuwen Sheng, et al. J Med Chem. 2022 Jan 13;65(1):460-484.

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