Pyruvate Carboxylase-IN-5 | Pyruvate carboxylase inhibitor

Chemical Structure : Pyruvate Carboxylase-IN-5

Pyruvate Carboxylase-IN-5 (Compound 6m)

Catalog No.: PC-27058Not For Human Use, Lab Use Only.

Pyruvate Carboxylase-IN-5 (Compound 6m) is a selective pyruvate carboxylase (PC) inhibitor with IC50 of 3.4 uM.

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Biological Activity

Pyruvate Carboxylase-IN-5 (Compound 6m) is a selective pyruvate carboxylase (PC) inhibitor with IC50 of 3.4 uM.
Pyruvate Carboxylase-IN-5 does not inhibit the metalloenzymes human carbonic anhydrase II and matrix metalloprotease-12, does not inhibit the related biotin-dependent enzyme, guanidine carboxylase.

Physicochemical Properties

M.Wt	294.24
Formula	C13H11FN2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl 2-(3-(4-fluorophenyl)-2,4,5-trioxoimidazolidin-1-yl)acetate

References

1. Nicholas O Schneider, et al. ACS Med Chem Lett. 2024 Jun 26;15(7):1088-1093.

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Pyruvate Carboxylase-IN-5 (Compound 6m)

Biological Activity

Physicochemical Properties

References

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