Chemical Structure : R-283
CAS No.: 135273-74-4
Catalog No.: PC-61734Not For Human Use, Lab Use Only.
R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM..
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R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM.
M.Wt | 220.715 | |
Formula | C8H13ClN2OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1,3-dimethyl-2-((2-oxopropyl)thio)-1H-imidazol-3-ium chloride |
1. Griffin M, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5559-62.
2. Freund KF, et al. Biochemistry. 1994 Aug 23;33(33):10109-19.
3. Miura A, et al. J Biol Chem. 2013 Nov 8;288(45):32720-30.
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