R-283 |CAS:135273-74-4 Probechem Biochemicals

Chemical Structure : R-283

CAS No.: 135273-74-4

Catalog No.: PC-61734Not For Human Use, Lab Use Only.

R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM.

M.Wt	220.715
Formula	C8H13ClN2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,3-dimethyl-2-((2-oxopropyl)thio)-1H-imidazol-3-ium chloride

1. Griffin M, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5559-62.

2. Freund KF, et al. Biochemistry. 1994 Aug 23;33(33):10109-19.

3. Miura A, et al. J Biol Chem. 2013 Nov 8;288(45):32720-30.