R-55 |CAS:2076-91-7 Probechem Biochemicals

Chemical Structure : R-55

R-55 (R 55;R55)

Catalog No.: PC-70004Not For Human Use, Lab Use Only.

A small molecule that stabilizes Retromer against thermal denaturation.

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Biological Activity

A small molecule that stabilizes Retromer against thermal denaturation; increases the levels of retromer proteins, shifts APP away from the endosome, and decreases the pathogenic processing of APP; has potential therapeutic implications for neurodegenerative diseases.

Physicochemical Properties

M.Wt	260.392
Formula	C8H12N4S3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	thiophene-2,5-diylbis(methylene) dicarbamimidothioate

References

1. Mecozzi VJ, et al. Nat Chem Biol. 2014 Jun;10(6):443-9.

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R-55 (R 55;R55)

Biological Activity

Physicochemical Properties

References

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