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R848

Chemical Structure : R848

CAS No.: 144875-48-9

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R848 (Resiquimod, S 28463)

Catalog No.: PC-20230Not For Human Use, Lab Use Only.

Resiquimod (R848) is a potent, dual TLR8 and TLR7 synthetic agonist, induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α, demonstrates potent anti-tumor and anti-viral properties.

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50 mg $138 In stock
100 mg $228 In stock
500 mg $428 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Resiquimod (R848) is a potent, dual TLR8 and TLR7 synthetic agonist, induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α, demonstrates potent anti-tumor and anti-viral properties.

Physicochemical Properties

M.Wt 314.39
Formula C17H22N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol

References

1. Bernstein, D.I.et al. J. Infect. Dis. 183(6), 844-849 (2001).

2. Bishop, G.A.,et al. J. Immunol. 165(10), 5552-5557 (2000).

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