Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Chemokine Receptor (CCR and CXCR)-RAMX3
RAMX3

Chemical Structure : RAMX3

CAS No.: 1397708-94-9

Add to Favorites

RAMX3 (RAMX-3;RAMX 3)

Catalog No.: PC-61172Not For Human Use, Lab Use Only.

RAMX3 is a tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
500 mg Get quote
1 g Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RAMX3 is a tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM.
    In radioligand displacement assays shows potent negative cooperativity between RAMX3 and chemokine CXCL11, providing a basis for the use of RAMX3 to investigate other potential allosteric modulators.

    Physicochemical Properties

    M.Wt 631.693
    Formula C33H32T3F4N5O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-((1-(methyl-t3)piperidin-4-yl)methyl)acetamide

    References

    1. Bernat V, et al. ACS Chem Biol. 2014 Nov 21;9(11):2664-77.

    2. Bernat V, et al. ChemMedChem. 2012 Aug;7(8):1481-9.

    3. Milanos L, et al. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15277-15281.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: