Chemical Structure : RG7112
CAS No.:
939981-39-2
RG7112
(RG-7112;RO5045337)
Catalog No. : PC-42750Not For Human Use, Lab Use Only.
RG7112 (RO5045337) is a potent and selective inhibitor of p53-MDM2 interaction, binds MDM2 with high affinity (Kd=11 nM).
Packing Price Stock Quantity 5 mg $98 In stock 0 1 2 3 4 5 10 mg $148 In stock 0 1 2 3 4 5 25 mg $258 In stock 0 1 2 3 4 5 50 mg $398 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4275001
Biological Activity
RG7112 (RO5045337) is a potent and selective inhibitor of p53-MDM2 interaction, binds MDM2 with high affinity (Kd=11 nM).
Physicochemical Properties
M.Wt
727.7831
Formula
C38H48Cl2N4O4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Methanone, [(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]-
References
1. Tovar C, et al. Cancer Res
2. Andreeff M, et al. Clin Cancer Res
3. Vu B, et al. ACS Med Chem Lett
Contact Us
sales@probechem.com
