RN-1665 | TRPV4 antagonist | Probechem Biochemicals

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Chemical Structure : RN-1665

CAS No.: 1803003-65-7

RN-1665 (RN1665)

Catalog No.: PC-26401Not For Human Use, Lab Use Only.

RN-1665 is a potent, selective and orally active TRPV4 antagonist with IC50 of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4, exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8.

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5 mg	$238	In stock
10 mg	$388	In stock
25 mg	$598	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	513.54
Formula	C20H24F5N3O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-((4-Isopropylpiperazin-1-yl)sulfonyl)phenyl)-4-(pentafluoro-l6-sulfaneyl)benzamide

References

1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5.

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RN-1665 (RN1665)

Biological Activity

Physicochemical Properties

References

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