Chemical Structure : RN-1734
CAS No.:
946387-07-1
RN-1734
(RN1734;RN 1734)
Catalog No. : PC-45772Not For Human Use, Lab Use Only.
RN-1734 (RN1734) is a potent, selective TRPV4 antagonist with IC50 of 2.3, 3.2 and 5.9 uM for hTRPV4, rTRPV4 and mTRPV4 channels, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4577201
Biological Activity
RN-1734 (RN1734) is a potent, selective TRPV4 antagonist with IC50 of 2.3, 3.2 and 5.9 uM for hTRPV4, rTRPV4 and mTRPV4 channels, respectively.
Physicochemical Properties
M.Wt
353.3077
Formula
C14H22Cl2N2O2S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 31 mg/mL
Chemical Name/SMILES
Benzenesulfonamide, 2,4-dichloro-N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]-
References
1. Vincent F, et al. Biochem Biophys Res Commun
2. Bagher P, et al. Proc Natl Acad Sci U S A
3. Wong PS, et al. Eur J Pharmacol.
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