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Chemical Structure : RN-9893
CAS No.: 1803003-68-0
Catalog No.: PC-70039Not For Human Use, Lab Use Only.
RN-9893 (RN9893) is a potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $178 | In stock | |
| 25 mg | $278 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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RN-9893 (RN9893) is a potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively.
RN-9893 shows >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets.
| M.Wt | 500.493 | |
| Formula | C21H23F3N4O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(4-((4-isopropylpiperazin-1-yl)sulfonyl)phenyl)-2-nitro-4-(trifluoromethyl)benzamide |
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1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5.
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