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Chemical Structure : RN-9893 hydrochloride
Catalog No.: PC-70040Not For Human Use, Lab Use Only.
RN-9893 hydrochloride is a potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively.
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RN-9893 hydrochloride is a potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively.
RN-9893 dispalys >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets.
| M.Wt | 536.95 | |
| Formula | C21H23F3N4O5S.HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5.
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