Chemical Structure : RPT193
CAS No.:
2366152-15-8
RPT193
(Zelnecirnon, RPT-193)
Catalog No. : PC-49464Not For Human Use, Lab Use Only.
RPT193 (Zelnecirnon, RPT-193) is a highly potent, selective and orally active CCR4 antagonist, inhibits CCL22- induces human Th2 chemotaxis with IC50 of 370 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4946401
Biological Activity
RPT193 (Zelnecirnon, RPT-193) is a highly potent, selective and orally active CCR4 antagonist, inhibits CCL22- induces human Th2 chemotaxis with IC50 of 370 nM.
Physicochemical Properties
M.Wt
566.95
Formula
C27H34Cl3N5O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
trans-3-[(3R)-3-[1-[5-Chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methyl-2-pyrimidinyl]-3-azetidinyl]-1-piperidinyl]-1-methylcyclobutanecarboxylic acid
References
1. Robert Bissonnette, et al. Allergy.
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