RR-11055 | Cereblon ligand | Probechem Biochemicals

Chemical Structure : RR-11055

Catalog No.: PC-24556Not For Human Use, Lab Use Only.

RR-11055 is a potent and novel cereblon (CRBN) ligand with binding IC50 of 0.38 uM, is useful for the development efficacious PROTAC degrader.

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Biological Activity

RR-11055 is a potent and novel cereblon (CRBN) ligand with binding IC50 of 0.38 uM, is useful for the development efficacious PROTAC degrader.

M.Wt	356.38
Formula	C18H20N4O4:
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-((R)-1-Oxo-1,3,5,5a,6,7,8,9-octahydro-2H-pyrazino[1',2':4,5][1,4]oxazino[2,3-e]isoindol-2-yl)piperidine-2,6-dione

1. Acharyya RK, et al. J Med Chem. 2024 Nov 14;67(21):19010-19037.

2. Patent WO2024015340.