Chemical Structure : RR6
CAS No.: 1351758-37-6
Catalog No.: PC-45557Not For Human Use, Lab Use Only.
RR6 is a selective, reversible, and competitive Vanin inhibitor with IC50 of 0.54 uM for hVVN1 pantetheinase.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $238 | In stock | |
10 mg | $358 | In stock | |
25 mg | $528 | In stock | |
100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
RR6 is a selective, reversible, and competitive Vanin inhibitor with IC50 of 0.54 uM for hVVN1 pantetheinase.
RR6 completely inhibits plasma vanin activity and caused alterations of plasma lipid concentrations in rats.
RR6 inhibits PDGF-induced SMC proliferation and protects SMCs from TNF-α-induced apoptosis in vitro, attenuates transplant vasculopathy in rat aortic allografts; orally bioactive.
M.Wt | 293.3581 | |
Formula | C16H23NO4 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
Butanamide, 2-hydroxy-3-(hydroxymethyl)-3-methyl-N-(3-oxo-4-phenylbutyl)-, (2R)- |
1. Jansen PA, et al. ACS Chem Biol. 2013 Mar 15;8(3):530-4.
2. van Diepen JA, et al. Sci Rep. 2016 Mar 2;6:21906.
3. Wedel J, et al. Transplantation. 2016 Aug;100(8):1656-66.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright