RR601 | DUSP5 inhibitor | Probechem Biochemicals

Chemical Structure : RR601

RR601 (RR 601, RR-601)

Catalog No.: PC-61175Not For Human Use, Lab Use Only.

RR601 is a potent, selective protein tyrosine phosphatase DUSP5, PTP1B and SHP-2 inhibitor with IC50 of 36 uM, 2.1 uM and 1.1 uM respectively, 8-fold selectivity for PTP1B versus DUSP5.

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Biological Activity

RR601 is a potent, selective protein tyrosine phosphatase DUSP5, PTP1B and SHP-2 inhibitor with IC50 of 36 uM, 2.1 uM and 1.1 uM respectively, 8-fold selectivity for PTP1B versus DUSP5.
RR601 has IC50 of 4.8 uM in pERK assays.

Physicochemical Properties

M.Wt	518.422
Formula	C20H12N2Na2O8S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	sodium (E)-8,8'-(diazene-1,2-diyl)bis(4-hydroxynaphthalene-2-sulfonate)

References

1. Bongard RD, et al. BMC Biochem. 2017 May 31;18(1):10.

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RR601 (RR 601, RR-601)

Biological Activity

Physicochemical Properties

References

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