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Chemical Structure : RTOXA-43
Catalog No.: PC-20563Not For Human Use, Lab Use Only.
RTOXA-43 is a potent, dual orexin receptor agonist with EC50 of 24 nM at both OX2R and OX1R.
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RTOXA-43 is a potent, dual orexin receptor agonist with EC50 of 24 nM at both OX2R and OX1R.
RTOXA-43 (40 mg/kg, i.p.) increased time awake, decreased time asleep and increased sleep/wake consolidation when measured using continuous EEG/EMG recordings in 12-month old mice.
| M.Wt | 663.79 | |
| Formula | C37H37N5O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dehui Zhang, et al. J Med Chem. 2021 Jun 24;64(12):8806-8825.
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