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RU-NT-206

Chemical Structure : RU-NT-206

CAS No.: 1038304-09-4

RU-NT-206

Catalog No.: PC-21807Not For Human Use, Lab Use Only.

RU-NT-206 is a small molecule inhibitor targeting the P-stalk binding pocket of ricin toxin A subunit (RTA) with IC50 of 7 uM, inhibits catalytic activity and protects cells against ricin and Stx2 holotoxins.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RU-NT-206 is a small molecule inhibitor targeting the P-stalk binding pocket of ricin toxin A subunit (RTA) with IC50 of 7 uM, inhibits catalytic activity and protects cells against ricin and Stx2 holotoxins.

Physicochemical Properties

M.Wt 258.34
Formula C15H14O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5,5-dimethyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid

References

1. Michael J Rudolph, et al. Bioorg Med Chem. 2024 Feb 15:100:117614.

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