Chemical Structure : RUNX1-IN-17
Catalog No.: PC-61298Not For Human Use, Lab Use Only.
A potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays; binds to CBFβ at a site displaced from the binding interface for Runx1; decreases proliferation in human leukemia cell line ME-1.
M.Wt | 234.317 | |
Formula | C12H14N2OS | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
1. Gorczynski MJ, et al. Chem Biol. 2007 Oct;14(10):1186-97.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright