Cat. No. |
Product Name |
Information |
PC-61299 |
AI-10-104
RUNX1-CBFβ inhibitor
|
AI-10-104 is a small molecule inhibitor that interferes with CBFβ binding to RUNX proteins with IC50 of 1.25 uM in FRET assays. |
PC-61298 |
RUNX1-IN-17
RUNX1-CBFβ inhibitor
|
RUNX1-IN-17 is a potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays. |
PC-70219 |
Ro5-3335
RUNX1-CBFβ inhibitor
|
Ro5-3335 is a small molecule RUNX1-CBFβ interaction inhibitor that represses RUNX1/CBFB-dependent transactivation |
PC-45078 |
AI-10-49
RUNX1-CBFβ inhibitor
|
AI-10-49 is a potent (FRET IC50=260 nM) RUNX-CBFβ protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1. |