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RXFP3 agonist 10d

Chemical Structure : RXFP3 agonist 10d

CAS No.: 2752378-78-0

RXFP3 agonist 10d

Catalog No.: PC-49432Not For Human Use, Lab Use Only.

RXFP3 agonist 10d is a potent, selective, nonpeptide dual RXFP3/4 agonist with EC50 of 3.1/2.7 nM, no agonist activity against RXFP1 at 10 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RXFP3 agonist 10d is a potent, selective, nonpeptide dual RXFP3/4 agonist with EC50 of 3.1/2.7 nM, no agonist activity against RXFP1 at 10 uM.

    Physicochemical Properties

    M.Wt 402.458
    Formula C22H22N6O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    methyl (E)-4-(2-(2-((5-cyano-7-methyl-1H-indol-3-yl)methylene)hydrazine-1-carboximidamido)ethyl)benzoate

    References

    1. Dongliang Guan, et al. J Med Chem. 2021 Dec 23;64(24):17866-17886.

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