| Cat. No. |
Product Name |
Information |
| PC-20022 |
DC591053
RXFP4 agonist
|
DC591053 (DC 591053) is a selective small molecule agonist of relaxin family peptide receptor 4 (RXFP4) with pEC50 of 7.24 and pKi of 6.95, shows no activity against RXFP3. |
| PC-49433 |
RXFP3/4 agonist 4
RXFP3/4 agonist
|
RXFP3/4 agonist 4 is a potent, selective, nonpeptide dual RXFP3/4 agonist with EC50 of 82/2.0 nM in cellualr cAMP assays. |
| PC-49432 |
RXFP3 agonist 10d
RXFP3/4 agonist
|
RXFP3 agonist 10d is a potent, selective, nonpeptide dual RXFP3/4 agonist with EC50 of 3.1/2.7 nM, no agonist activity against RXFP1 at 10 uM. |
| PC-49427 |
RXFP2 agonist 6641
FXRP2 agonist
|
RXFP2 agonist 6641 is a highly potent, selective and full allosteric agonist of relaxin/insulin-like family peptide receptor 2 (RXFP2) with EC50 of 0.38 uM, Emax=107% (hFXRP2). |
| PC-49353 |
AZD5462
RXFP1 agonist
|
AZD5462 (AZD-5462) is a selective, allosteric, oral agonist of the Relaxin family peptide receptor 1 (RXFP1) with pEC50 of 7.8 (hRXFP1). |
| PC-38726 |
RLX-33
RXFP3 antagonist
|
RLX-33 is a selective small-molecule nonpeptide antagonist of neuropeptide relaxin-3/RXFP3 with IC50 of 2.36 uM (cAMP functional assays), selective for RXFP3 over RXFP1 and RXFP4. |
| PC-70187 |
ML-290
RXFP1 agonist
|
ML-290 (ML290) is a potent and selective small-molecule agonist of hRXFP1 with EC50 of 94 nM. |
| PC-22502 |
GSK618069
FXRP2 antagonist
|
GSK618069 is a potent, selective antagonist of relaxin family peptide receptor 2 (RXFP2) with IC50 of 0.4 uM in HEK-hRXFP2 cAMP assays, 200-fold reduced potency against rRXFP2. |
| PC-22033 |
AZ7976
RXFP1 agonist
|
AZ7976 (AZ-7976) is a potent, highly selective, allosteric relaxin family peptide receptor 1 (RXFP1) agonist with pEC50 of 9.4 in hRXFP1 cAMP assay in CHO-K1 cells, Emax=114%. |
