RXR agonist V-125

Chemical Structure : RXR agonist V-125

CAS No.: 1807740-94-8

Catalog No.: PC-26026Not For Human Use, Lab Use Only.

RXR agonist V-125 is a potent, selective next-generation RXR agonist with EC50 of 14 nM (RXRα activation).

Packing	Price	Stock
10 mg	$78	In stock
25 mg	$128	In stock
50 mg	$198	In stock
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Biological Activity

RXR agonist V-125 is a potent, selective next-generation RXR agonist with EC50 of 14 nM (RXRα activation).
V-125 reduces lung tumor burden in A/J mice.
V-125 delays the development of HER2-positive mammary tumors in MMTV-Neu mice.
V-125 alters immune-related biomarkers in MMTV-Neu tumors.
V-125 differentially regulates cancer-associated genes in tumors.

Physicochemical Properties

M.Wt	366.51
Formula	C23H30N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino)nicotinic acid

References

1. Reich LA, et al. Sci Rep. 2022 Jan 7;12(1):293.

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RXR agonist V-125

Biological Activity

Physicochemical Properties

References

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