Chemical Structure : RapaLink-1
CAS No.: 1887095-82-0
Catalog No.: PC-60418Not For Human Use, Lab Use Only.
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors.
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RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors.
RapaLink-1 blocks mTOR signaling of the F2108L mTOR and M2327I mTOR drug resistant mutants.
RapaLink-1 is more potent mTOR inhibitor than rapamycin.
| M.Wt | 1784.165 | |
| Formula | C91H138N12O24 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
40-O-(2-((1-(32-(4-amino-3-(2-aminobenzo[d]oxazol-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-27-oxo-3,6,9,12,15,18,21,24-octaoxa-28-azadotriacontyl)-1H-1,2,3-triazol-4-yl)methoxy)ethyl)-rapamycin |
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1. Rodrik-Outmezguine VS, et al. Nature. 2016 Jun 9;534(7606):272-6.

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