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Ras binder compound 3

Chemical Structure : Ras binder compound 3

CAS No.: 2230185-88-1

Ras binder compound 3 (Ras inhibitor)

Catalog No.: PC-38332Not For Human Use, Lab Use Only.

Ras binder compound 3 is a switch-II binding ligand which binds Ras GDP and GTP states, inhibits PI3K activation in vitro.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Ras binder compound 3 is a switch-II binding ligand which binds Ras GDP and GTP states, inhibits PI3K activation in vitro.

    Physicochemical Properties

    M.Wt 464.829
    Formula C21H16ClF3N4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3-acrylamido-5-chlorophenyl)-1-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide

    References

    1. Daniel R Gentile, et al. Cell Chem Biol. 2017 Dec 21;24(12):1455-1466.e14.

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