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Raseglurant hydrochloride

Chemical Structure : Raseglurant hydrochloride

CAS No.:

Raseglurant hydrochloride (ADX10059, ADX-10059)

Catalog No.: PC-27656Not For Human Use, Lab Use Only.

Raseglurant hydrochloride (ADX10059) is a selective metabotropic glutamate type 5 (mGlu5) receptor negative allosteric modulator (mGlu5 NAM), shows potential for treatment of neuropathic pain and migraine.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Raseglurant hydrochloride (ADX10059) is a selective metabotropic glutamate type 5 (mGlu5) receptor negative allosteric modulator (mGlu5 NAM), shows potential for treatment of neuropathic pain and migraine.

Physicochemical Properties

M.Wt 276.74
Formula C15H14ClFN2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((3-Fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-amine hydrochloride

References

1. Font J, et al. Elife. 2017 Apr 11;6:e23545.

2. Romero-Fernandez W, et al. Mol Neurobiol. 2022 Oct;59(10):5955-5969.

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