Ratutrelvir | SARS-CoV-2 Mpro inhibitor

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Chemical Structure : Ratutrelvir

Ratutrelvir (Travatrelvir, 83-0060, TRX01)

Catalog No.: PC-24173Not For Human Use, Lab Use Only.

Ratutrelvir (Travatrelvir, 83-0060, TRX01) is a potent, selective inhibitor of SARS-CoV-2 main protease Mpro (3CL protease).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Ratutrelvir (Travatrelvir, 83-0060, TRX01) is a potent, selective inhibitor of SARS-CoV-2 main protease Mpro (3CL protease).
Ratutrelvir has demonstrated in vitro activity against the original strain of the virus as well as the delta and omicron variants and is more active than nirmatrelvir in preclinical studies.

Physicochemical Properties

M.Wt	547.58
Formula	C27H32F3N5O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[(1S)-1-cyano-2-(2,3-dihydro-2-oxo-1H-indol-3-yl)ethyl]-3-[(2S)-3,3-dimethyl-1-oxo-2-[(2,2,2-trifluoroacetyl)amino]butyl]-6,6-dimethyl-, (1R,2S,5S)-

References

1. Patent WO2023245162 A2.

2. Patent WO2023093834 A1.

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Ratutrelvir (Travatrelvir, 83-0060, TRX01)

Biological Activity

Physicochemical Properties

References

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