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Chemical Structure : Rbin-1
CAS No.: 328023-11-6
Catalog No.: PC-42264Not For Human Use, Lab Use Only.
Rbin-1 (Ribozinoindole-1) is a potent, specific and reversible inhibitor of eukaryotic ribosome biogenesis that targets the AAA+ protein Midasin (IC40=1 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Rbin-1 (Ribozinoindole-1) is a potent, specific and reversible inhibitor of eukaryotic ribosome biogenesis that targets the AAA+ protein Midasin (IC40=1 uM).
Rbin-1 inhibits the cell growth Wild-type fission yeast strains with GI50 of 136 nM, reduces the levels of Mdn1 in the Nsa1 particle.
Rbin-1 is a powerful probe for eukaryotic ribosome assembly.
| M.Wt | 256.3262 | |
| Formula | C13H12N4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
5H-1,2,4-Triazino[5,6-b]indole, 3-[(2-methyl-2-propen-1-yl)thio]- |
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1. Kawashima SA, et al. Cell. 2016 Oct 6;167(2):512-524.e14.
2. Garbarino JE, et al. BMC Genomics. 2002;3:18.
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