Rebaudioside N

Chemical Structure : Rebaudioside N

CAS No.: 1220616-46-5

Catalog No.: PC-26275Not For Human Use, Lab Use Only.

Rebaudioside N is a terpenoid glycoside isolated from the leaves of Stevia rebaudiana Bertoni, is a potent SH3 domain-binding kinase 2 (SBK2) agonist, effectively suppresses NLRP3-mediated IL-1β/IL-18 secretion, reduces inflammatory responses, and diminishes atherosclerotic burden.

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Biological Activity

Physicochemical Properties

M.Wt	1275.30
Formula	C56H90O32
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3R,4S,5R,6R)-5-Hydroxy-6-(hydroxymethyl)-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl (4R,4aS,6aR,9S,11aR,11bS)-9-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalen

References

1. Schiffman SS, et al. Physiol Behav. 1994 Mar;55(3):547-59.

2. Ibrahim MA, et al. J Nat Prod. 2014 May 23;77(5):1231-5.

3. Cai L, et al. Eur Heart J. 2026 Feb 13:ehag047.

Rebaudioside N

Biological Activity

Physicochemical Properties

References

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