Catalog No.: PC-43483Not For Human Use, Lab Use Only.
Regorafenib hydrochloride (BAY73-4506) is a potent, orally active multikinase inhibitor that potently inhibits endothelial cell kinases in biochemical and cellular kinase phosphorylation assays with nanomolar range (IC50=3-200 nM).
Regorafenib hydrochloride (BAY73-4506) is a potent, orally active multikinase inhibitor that potently inhibits endothelial cell kinases in biochemical and cellular kinase phosphorylation assays with nanomolar range (IC50=3-200 nM).
Regorafenib hydrochloride inhibits VEGFR1/2/3, PDGFRβ, FGFR1, KIT, RET and B-RAF etc.
Regorafenib hydrochloride exhibits potent dose-dependent TGI in various preclinical human xenograft models in mice.
