Chemical Structure : Rhoifolin
CAS No.: 17306-46-6
Catalog No.: PC-27550Not For Human Use, Lab Use Only.
Rhoifolin is a natural flavonoid with anti-inflammatory and antiparasitic potential, is a a direct potassium channel modulatory factor 1 (KCMF1) binder that stabilizes AMPKα and ameliorates MASLD, also inhibits the specific binding site of ALDH2-PKCδ, significantly increases chemosensitivity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $78 | In stock | |
| 50 mg | $118 | In stock | |
| 100 mg | Get quote |
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Rhoifolin is a natural flavonoid with anti-inflammatory and antiparasitic potential, is a a direct potassium channel modulatory factor 1 (KCMF1) binder that stabilizes AMPKα and ameliorates MASLD, also inhibits the specific binding site of ALDH2-PKCδ, significantly increases chemosensitivity.
Rhoifolin selectively potentiates ILC3s effector function without affecting their proliferation, apoptosis, intestinal homing, developmental differentiation, or the distribution of CCR6+, NKp46+, and double-negative ILC3s subsets, directly targets NMNAT1.
Rhoifolin inhibits ferroptosis and alleviates pulmonary arterial hypertension via the TNF-alpha/TNF-R1/CASP8/CASP3 pathway.
Rhoifolin targets leukemia stem cells (LSCs) within the bone marrow microenvironment, work synergistically with conventional chemotherapy drugs, and exhibit no toxicity toward normal cells.
| M.Wt | 578.52 | |
| Formula | C27H30O14 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
7-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
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1. Kenzerki RE, et al. Sci Rep. 2026 Jun 6. doi: 10.1038/s41598-026-56709-w.
2. Yang H, et al. Adv Sci (Weinh). 2026 Aug 7:e76935.
3. Tang M, et al. Metabolism. 2026 Sep;182:156651.
4. Deng S, et al. Phytomedicine. 2026 Jun;155:158095.

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