Risdiplam (RG7916, RO7034067) | SMN2 splicing modulator

Chemical Structure : Risdiplam

CAS No.: 1825352-65-5

Risdiplam (RG7916, RG-7916, RO7034067)

Catalog No.: PC-61397Not For Human Use, Lab Use Only.

Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA).

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
50 mg	$528	In stock
100 mg		Get quote

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Biological Activity

Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA).
RG7916 is undergoing clinical trials across the spectrum of spinal muscular atrophy, where it has shown promising early results.

Physicochemical Properties

M.Wt	401.474
Formula	C18H29N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

References

1. Mammas IN, et al. Exp Ther Med. 2018 Apr;15(4):3673-3679.

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Risdiplam (RG7916, RG-7916, RO7034067)

Biological Activity

Physicochemical Properties

References

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