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Rnaseh2c-In1

Chemical Structure : Rnaseh2c-In1

CAS No.: 1034736-09-8

Rnaseh2c-In1

Catalog No.: PC-26574Not For Human Use, Lab Use Only.

Rnaseh2c-In1 is a specific small molecule inhibits of ribonuclease H2 subunit C (Rnaseh2c), significantly inhibits the proliferation of HCC via Cdk9 proliferation axis and CCL2/CCR2-mediated CD8+ Tex infiltration.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Rnaseh2c-In1 is a specific small molecule inhibits of ribonuclease H2 subunit C (Rnaseh2c), significantly inhibits the proliferation of HCC via Cdk9 proliferation axis and CCL2/CCR2-mediated CD8+ Tex infiltration.

Physicochemical Properties

M.Wt 367.42
Formula C19H17N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-7-(3-hydroxy-4-methoxyphenyl)-2-(phenylamino)-6,7-dihydrothiazolo[4,5-b]pyridin-5(4H)-one

References

1. Zengbin Wang, et al. J Immunother Cancer. 2026 Apr 15;14(4):e014993.

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